diacerein

chelates with bivalent metals; a quinone which possesses redox properties; metabolized to active rhein; proposed mechanisms include inhibiting IL1 and metalloproteinases; called a slow acting symptomatic drug in osteoarthritis; no effect of cyclooxygenase;

Also Known As:

1,8-diacetoxy-3-carboxyanthraquinone; 2-anthracenecarboxylic acid, 4,5- bis(acetyloxy)- 9,10- dihydro- 9,10- dioxo- ; 4,5- bis(acetyloxy)- 9,10- dihydro- 9,10- dioxo- 2- anthracenecarboxylic acid; 4,5-diacetoxyanthraquinone-2-carboxylic acid; 9,10- dihydro- 4,5- dihydroxy- 9,10- dioxo- 2- anthroic acid, diacetate; AC-201; AC-203; Artrodar; Diora; Fisiodar; M-01AX21; M01AX21; SF-277; SF277; Verboril; Zondar; diacerhein; diacetyl-rhein; diacetylrhein; rhein diacetate

Pharmalogical Action Categories:

D000893 - Anti-Inflammatory Agents

Organic Chemicals: 140
- Hydrocarbons: 1726
  - Cyclic Hydrocarbons: 96
    - Aromatic Hydrocarbons: 295
      - Polycyclic Aromatic Hydrocarbons: 2081
        Anthracenes: 12
        Anthrones: 13
        Anthraquinones: 815
        diacerein: 270
- Quinones: 443
  - Anthraquinones: 815
    - diacerein: 270
Polycyclic Compounds: 7
- Polycyclic Aromatic Hydrocarbons: 2081
  - Anthracenes: 12
    - Anthrones: 13
      - Anthraquinones: 815
        diacerein: 270

DISSCO Trial Investigator Group Selected Research

DISSCO Trial Investigator Group Research Topics

Disease

Drug/Important Bio-Agent (IBA)